Pregnancy: Pregnancy category C.
Animal reproduction studies have not been performed with Phenylephrine. It is not known whether topically applied Phenylephrine can cause fetal harm when administered to pregnant women. Parenterally administered Phenylephrine in late pregnancy or labor may cause fetal anoxia. Topically applied Phenylephrine should be used during pregnancy only when clearly needed.
Lactation: Since it is not known whether Phenylephrine is distributed into milk, the drug should be used with caution in nursing women.