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Use in Pregnancy: As no clinical data on exposed pregnancies are available, Plavix should not be used during pregnancy, unless, in the opinion of the physician, there is a clear need. Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonic/foetal development, parturition or postnatal development (see Pharmacology: Toxicology under Actions).
Use in Lactation: Studies in rats have shown that clopidogrel and/or its metabolites are excreted in the milk. It is not known whether Plavix is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to a nursing woman.
