The information highlighted (if any) are the most recent updates for this brand.
Limited information is available on the acute overdosage of Flucytosine. Although there have been no reports to date of intentional overdosage of Flucytosine, the signs and symptoms of overdosage can be expected to produce pronounced manifestations of the known adverse effects of the drug. Prolonged serum Flucytosine concentrations greater than 100 mcg/mL may be associated with an increased incidence of toxicity, especially GI effects (diarrhea, nausea, vomiting), hematologic effects (leukopenia, thrombocytopenia), and hepatic effects (hepatitis). In the event of Flucytosine overdosage, the stomach should be emptied immediately by gastric lavage or an emetic. Adequate fluid intake should be maintained and IV fluid given if necessary. Hematologic parameters should be assessed frequently and liver and kidney function carefully monitored.
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