Infuse IV at initial rate of 0.46-0.92 mL/kg/hr for 20-30 min; may be increased gradually to a max of 1.85 mL/kg/hr.
Prevention of hepatitis B re-infection after liver transplantation for hepatitis B-induced liver failure Adult 10,000 IU on the day of transplantation perioperative; then 2,000-10,000 IU/day for 7 days & as necessary.
Childn 10,000 IU/1.73 m
2 BSA.
Immunoprophylaxis of hepatitis B: Prevention of hepatitis B in case of accidental exposure in non-immunised subjects At least 500 IU w/in 24-72 hr of exposure.
Immunoprophylaxis of hepatitis B in haemodialysis patients 8-12 IU/kg w/ a max of 500 IU every 2 mth until seroconversion following vaccination.
Immunoprophylaxis of hepatitis B: Prevention of hepatitis B in the newborn of a HBV carrier-mother, at birth or as soon as possible after birth 30-100 IU/kg. IM route is preferred whenever repeated administration is required to achieve seroconversion after vaccination.
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