Incompatibilities: In the absence of incompatibility studies, reconstituted XYNTHA should not be administered in the same tubing or container with other medicinal products. Infusion kit components supplied in the carton are compatible with XYNTHA for administration.
Special precautions for disposal and other handling: XYNTHA, when reconstituted, contains polysorbate-80, which is known to increase the rate of di-(2-ethylhexyl) phthalate (DEHP) extraction from polyvinyl chloride (PVC). This should be considered during the preparation and administration of XYNTHA, including storage time elapsed in a PVC container following reconstitution. It is important that the recommendations in Dosage & Administration be followed closely.