Jemperli Caution For Usage

Special precautions for disposal and other handling: Do not co-administer other medicinal products through the same infusion line.
Any unused medicinal product or waste material should be disposed of in accordance with local requirements.
Preparation/dilution: Parenteral medicinal products should be inspected visually for particulate matter and discolouration prior to administration. Dostarlimab is a slightly opalescent colourless to yellow solution. Discard the vial if visible particles are observed.
For the 500 mg dose, withdraw 10 mL of dostarlimab from a vial and transfer into an intravenous bag containing sodium chloride 9 mg/mL (0.9%) solution for injection, or glucose 50 mg/mL (5%) solution for injection. The final concentration of the diluted solution should be between 2 mg/mL and 10 mg/mL.
For the 1,000 mg dose, withdraw 10 mL of dostarlimab from each of two vials (withdraw 20 mL total) and transfer into an intravenous bag containing sodium chloride 9 mg/mL (0.9%) solution for injection, or glucose 50 mg/mL (5%) solution for injection. The final concentration of the diluted solution should be between 2 mg/mL and 10 mg/mL.
Mix diluted solution by gentle inversion. Do not shake the final infusion bag. Discard any unused portion left in the vial.
Incompatibilities: In the absence of compatibility studies, this medicinal product must not be mixed with other medicinal products.