Zeldox Dosage/Direction for Use

Use of Ziprasidone Capsules: For oral use. Capsules should be taken with food and swallowed whole without chewing, crushing or opening beforehand..
Use in Adults: Schizophrenia and Bipolar Mania: The recommended initial dose is 40 mg twice daily, to be taken with food (See Pharmacology: Pharmacokinetics under Actions). Daily dosage may subsequently be adjusted on the basis of individual clinical status up to a maximum of 80 mg twice daily. If indicated, the maximum recommended dose may be reached as early as Day 3 of treatment.
Use in Children: Safety and effectiveness in children under 18 years have not been established.
Use in the Elderly: Generally, no dosage adjustment is required in elderly patients (65 years and over).
Use in Renal Impairment: No dosage adjustment is required in patients with renal impairment.
Use in Hepatic Impairment: In patients with mild to moderate hepatic insufficiency, lower doses should be considered. There is a lack of experience in patients with severe hepatic insufficiency and ziprasidone should be used with caution in this group (See Pharmacology: Pharmacokinetics under Actions).
Use in Smokers: No dosage adjustment is required in patients who smoke.
Bipolar I Disorder: Acute Treatment of Manic or Mixed Episodes: The recommended initial dose is 40 mg twice daily, to be taken with food. Daily dosage may subsequently be adjusted on the basis of individual clinical status up to a maximum of 80 mg twice daily. If indicated, the maximum recommended dose may be reached as early as Day 3 of treatment.
Maintenance Treatment (as an adjunct to lithium or valproate): Continue treatment at the same dose on which the patient was initially stabilized, within the range of 40 mg - 80 mg twice daily with food. Patients should be periodically reassessed to determine the need for maintenance treatment.