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Most adverse effects of salbutamol in pregnancy relate to the cardiovascular and metabolic effects of the very high doses given by intravenous infusion to delay premature labor.
The use of salbutamol in lactating mothers is generally not recommended since it is not known whether salbutamol in breast milk has harmful effects on the neonate.
Pulmonary edema has been reported in pregnant women given with salbutamol for premature labor, although most cases are seen in patients given very high doses intravenously. Maternal effects include myocardial ischemia, unifocal ventricular ectopics associated with the hypoischemic response to intravenous salbutamol and heart failure in hypersensitive woman.
