Ampimax Adverse Reactions

It is generally well tolerated. The following adverse reactions have been reported.
Systemic Adverse Reaction: Adverse reactions were diarrhea in 3% of the patients and rash in less than 2% of the patients. Additional systemic reactions reported in literature in less than 1% of the patients were itching, nausea, vomiting, candidiasis, fatigue, malaise, headache, chest pain, flatulence, abdominal distension, glossitis, urine retention, dysuria, edema, facial swelling, erythema, chills, tightness in throat, substernal pain, epistaxis and mucosal bleeding.
The following adverse reactions have been reported with Ampicillin class antibiotics and can also occur with Sulbactam Sodium/Ampicillin Sodium.
Gastrointestinal: Gastritis, stomach, black hairy tongue, enterocolitis and pseudomembranous colitis. Occasionally, elevation in liver enzyme levels have been reported which revert to normal on discontinuation of the drug.
Hypersensitivity Reactions: Urticaria, erythema multiforme and occasional case of exfoliative dermatitis have been reported. These reactions may be controlled with antihistamines and if necessary systemic corticosteroids. Whenever such reactions occur, the drug should be discontinued, unless the opinion of the physician dictates otherwise. Serious and occasional fatal hypersensitivity (anaphylactic) reactions can occur with penicillin.
Hematologic: In addition to the adverse laboratory changes like fall in hemoglobin levels, hematocrit and increase in leukocyte count has been reported during therapy with penicillins. All of these reactions are usually reversible on discontinuation of therapy and are believed to be hypersensitivity phenomena.