Patients w/ chronic or recurrent infection; who have been exposed to TB; w/ history of serious or opportunistic infection; resided or travelled in areas of endemic TB or endemic mycoses or w/ underlying conditions that may predispose to infection. Patients should be screened for TB before starting therapy & consider yrly TB screening in highly endemic areas. Viral reactivation including herpes virus (eg, herpes zoster/simplex). Avoid use of live, attenuated vaccines during or immediately prior to treatment. DVT & pulmonary embolism. Malignancies including non-melanoma skin cancer. Hematological abnormalities.CV risk factors including hyperlipidemia. Monitor CBC including platelet count, ALC, ANC & Hb, lipid parameters before initiation of treatment. Patients who experience dizziness after therapy should refrain from driving or using machines until dizziness resolves. Women of childbearing potential. Pregnancy & lactation. Childn ≥12 yr.
Sign Out
