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Special Precautions for Handling and Disposal: Upon preparations, solutions may show haziness, which is attributed to the formulation vehicle, and is not removed by filtration. Paclitaxel should be administered through an in-line filter with a microporous membrane ≤0.22 µm. No significant losses in potency have been noted following simulated delivery of the solution through IV tubing containing an in-line filter.
Dilution should be carried out under aseptic conditions by trained personnel in a designated area. Adequate protective gloves should be worn. Precautions should be taken to avoid contact with the skin and mucous membranes.
