Paclitaxel is contraindicated in patients who have a history of hypersensitivity to the active substance or to any of the excipients, especially Polyoxyethylated 35 castor oil (Macrogolglycerol ricinoleate 35). Lactation and patients with baseline neutrophils < 1,500/mm3 (<1,000/mm3 for KS patients) is also contraindicated.
In KS, Paclitaxel is contraindicated in patients with concurrent, serious, uncontrolled infections.