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Losartan Potassium is used in the management of hypertension and may have a role in patients who develop cough with Angiotensin Converting Enzyme inhibitors and to reduce the risk of stroke in patients with left ventricular hypertrophy, and in the treatment of diabetic nephropathy.
Hydrochlorothiazide is used in the treatment of edema associated with heart failure and with renal hepatic disorders. It is used in hypertension, either alone or together with other antihypertensives such as Angiotensin Converting Enzyme inhibitors and beta blockers.
Hydrochlorothiazide is also indicated in the treatment of edema accompanying premenstrual syndrome, prevention of water retention associated with corticosteroids and estrogens, treatment of diabetes insipidus, and prevention of renal calculus formation in patients with hypercalciuria.
