Fluimucil Drug Interactions

Drug-Drug Interactions: Drug interaction studies have been performed in adults only.
Antitussive drugs and mucolytic agents like acetylcysteine should not be concurrently administered because the reduction in cough reflex could lead to accumulation of bronchial secretions.
Concurrent administration of nitroglycerin and Acetylcysteine has been shown to cause significant hypotension and enhance temporal artery dilation. If concurrent nitroglycerin and Acetylcysteine therapy is necessary, patients should be monitored for hypotension, which can be severe, and warned of the possibility of headaches.
Concurrent use of acetylcysteine and carbamazepine may result in subtherapeutic carbamazepine levels.
Dissolution of acetylcysteine formulations concomitantly with other drugs is not recommended.
Reports of an inactivation of antibiotics resulting from acetylcysteine so far only relate to in-vitro tests in which the relevant substances were mixed directly. Nevertheless, when other oral drugs or antibiotics are required, it is advisable to administer the drugs 2 hours apart from acetylcysteine. This does not relate to loracarbef.
Activated charcoal may reduce the effect of acetylcysteine.
Drug-Lab Modifications: Acetylcysteine may interfere with colorimetric assay method for salicylate measurement. Acetylcysteine may interfere with urine ketone test.