Fluimucil Special Precautions

Mucolytic agents can induce respiratory obstruction in children under 2 years of age. Due to the physiological characteristics of the airways in this age group, the ability to expectorate may be limited. Therefore, mucolytic agent should not be used in children under 2 years of age. (See Contraindications.)
It should be used with caution in asthmatic patients and patients with a history of peptic ulceration especially in case of concomitant administration of other medicines with a known irritating effect on the gastric mucosa.
Patients suffering from bronchial asthma must be strictly monitored during the therapy. Should bronchospasm occurs, the treatment must be discontinued immediately and appropriate treatment must be initiated.
The administration of acetylcysteine, mainly at the start of treatment might fluidify bronchial secretion and increase their volume. If the patient is not able to effectively expectorate, postural drainage and bronchoaspiration should be performed.
Acetylcysteine may moderately affect histamine metabolism, therefore caution should be used when administering the product for long-term therapy in patients with histamine intolerance, since symptoms of intolerance can occur (headache, vasomotor rhinitis, itching).
The possible presence of sulfurous smell is not indicative of product alterations but is a characteristic of the active ingredient contained in this preparation.
It is preferred not to mix other drugs with Acetylcysteine (Fluimucil) solution.
Acetylcysteine (Fluimucil) Granules contain sorbitol. Patients with rare hereditary problems of fructose intolerance should not take this medicine.
Acetylcysteine (Fluimucil) Effervescent Tablet contains 6.8 mmol (or 156.9 mg) sodium per tablet. This must be taken into consideration by patients on a controlled sodium diet.
Acetylcysteine (Fluimucil) Granules and Acetylcysteine (Fluimucil) Effervescent Tablet contain aspartame, a source of phenylalanine. May be harmful for people with phenylketonuria.
Effects on the Ability to Drive and Use Machines: Acetylcysteine has no known influence on the ability to drive and use machines.