Gastro-Intestinal: gastritis, stomatitis, glossitis, black "hairy" tongue, enterocolitis and pseudomembranous colitis.
Hypersensitivity: skin rashes, urticaria, erythema multiforme, rare cases of Stevens-Johnson syndrome and less frequently exfoliate dermatitis and toxic epidermal necrolysis have been reported. Whenever such reactions occur Clavulanate Potassium and Amoxicillin should be discontinued. Serious and occasional fatal hypersensitivity (anaphylactic) reactions and angioneurotic oedema can occur with oral penicillin.
Haematopoietic and lymphatic: Anaemia, thrombocytopenia, thrombocytopenic, purpura, eosinophilia, leucopenia and agranulocytosis have been reported during therapy with penicillin. These reactions are usually reversible on discontinuation of therapy and are believed to be hypersensitivity phenomena. A slight thrombocytosis was noted less than 1% of the patients treated with Clavulanate Potassium and Amoxicillin. Prolongation of bleeding time and prothrombin time have been reported less frequently.
View ADR Monitoring Form