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Clavulanate Potassium and Amoxicillin should be given with caution to patients with lymphatic leukaemia since they are especially susceptible to Amoxicillin induced skin rashes. The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur (usually involving Aerobacter, Pseudomonas or Candida), the agent should be discontinued and/or appropriate therapy instituted.
Impaired hepatic function: Changes in liver function tests have been observed in some patients receiving Clavulanate Potassium and Amoxicillin. It should be used with care in patients with evidence of severe hepatic dysfunction.
Impaired renal function: In patients with moderate or severe renal impairment Clavulanate Potassium and Amoxicillin dosage should be adjusted.
