Gouter Dosage/Direction for Use

If Colchicine is used for acute attacks of gout, then treatment should be started as soon as possible and an effect may be expected within 12 hours. The recommended oral dose is 1 mg initially then 0.5 mg every 2 to 3 hours until pain relief is obtained or gastrointestinal adverse effects occur; the total dose should not exceed 10 mg. At least 3 days should elapse before another course is given. The dose by mouth is 0.5 to 1.2 mg initially, then 0.5 or 0.6 mg every 1 to 2 hours or 1 to 1.2 mg every 2 hours until pain is relieved or gastrointestinal adverse effects occur; the maximum total dose is 6 mg. Colchicine has sometimes been given intravenously in a dose of 1 or 2 mg over 2 to 5 minutes with additional doses of 0.5 or 1 mg every 6 to 24 hours as required to a total dose of not more than 4 mg in one course; once this amount of Colchicine has been given, further doses should not be given by any route for at least 7 days.
When used for the short-term prophylaxis of gout, doses by mouth are 0.5 or 0.6 mg once to three times daily.
Consideration should be given to using reduced dosages in patients with mild to moderate renal impairment.
Or as prescribed by the physician.