Pregnancy: There are no known harmful effects with supplementation with vitamins B1, B6, B12 or E during pregnancy.
Lactation: Vitamins B1, B6, B12 and E are expressed in breastmilk. There are no known harmful effects to the breastfeeding mother or breastfed infants with supplementation with vitamin B1, B6, B12 or E. Very large doses of vitamin B6, however, have been reported to suppress lactation.