Severe keratitis in adults w/ dry eye disease which has not improved despite treatment w/ tear substitutes. Severe vernal keratoconjunctivitis (VKC) in childn & adolescent 4-18 yr.
Severe keratitis in dry eye diseaseAdult 1 drop once daily to the affected eye(s) at bedtime. Do not instill >1 drop in the affected eye. Severe VKCAdolescent & childn >4 yr 1 drop qid (morning, noon, afternoon & evening) to each affected eye. If signs & symptoms persist after the end of the season, treatment can be maintained at the recommended dose or decreased to 1 drop bid once adequate control of signs & symptoms is achieved. Use nasolacrimal occlusion & close eyelids for 2 min after instillation. If >1 topical ophth medicinal product is being used, administer at least 15 min after all other ophth drops.
In treatment of severe keratitis in dry eye disease: Patients w/ history of ocular herpes; glaucoma. Monitor patients w/ severe keratitis. Concomitant w/ β-blockers. May affect host defenses against infections & malignancies. Remove contact lenses before instillation. In treatment of severe VKC: Active orofacial herpes simplex infection, history of ocular herpes, varicella-zoster or vaccinia virus infection. Not recommended to wear contact lenses. Co-administration w/ corticosteroids. May affect host defenses against infections & malignancies. Contains cetalkonium Cl which may cause eye irritation. Moderate influence on the ability to drive & use machines. Not recommended during pregnancy & in women of childbearing potential. Lactation. Childn & adolescents <18 yr.
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