HTN 50 mg, may be increased to 100 mg/day once or in 2 divided doses. Diabetic nephropathy Initially 50 mg/day, may be increased to 100 mg. Patient w/ hepatic impairment Initially 25 mg. Elderly w/o hepatic insufficiency 50 mg daily, may be increased to 100 mg/day in 2 divided doses. Moderate to severe renal impairment, intravascular or salt depletion 25 mg/day.
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