Pregnancy and hypersensitivity to losartan and any component of Kardiostan.
Use in pregnancy: Use of losartan during the 2nd and 3rd trimester of pregnancy may cause low blood pressure or severe kidney failure and is harmful, if not fatal to the fetus or infant. A case of oligohydramnios (decreased amniotic fluid), fetal effects and subsequent fetal death were reported in a patient exposed to losartan during 20-31 weeks of pregnancy. Treatment with losartan should be discontinued with the 1st sign of pregnancy.