Lacidipine should be used with caution in patients with hypotension, in patients whose cardiac reserve is poor, and in those with heart failure since deterioration of heart failure has been noted. Lacidipine should not be used in cardiogenic shock, in patients who have recently suffered a myocardial infarction, or in acute unstable angina. Lacidipine should not be used to treat an anginal attack in chronic stable angina. In patients with severe aortic stenosis lacidipine may increase the risk of developing heart failure. Sudden withdrawal of lacidipine might be associated with an exacerbation of angina. The dose may need to be reduced in patients with hepatic impairment.
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