![](https://mpfshstrg.blob.core.windows.net/mpf-uat-common-resources/Images/monograph/table.gif)
For felodipine the following undesirable effects have also been reported: (See Table 2).
![](https://mpfshstrg.blob.core.windows.net/mpf-uat-common-resources/Images/monograph/table.gif)
Isolated cases of confusion of sleep disturbance have been reported, but a connection with felodipine could not definitely be established.
Cases of gingival hyperplasia have been described after treatment with felodipine in patients with pronounced gingivitis/parodontitis. The swelling may be avoided or reduced by means of careful oral hygiene. Hyperglycemia is considered to be a group-specific adverse reaction, but for felodipine has been reported only in isolated cases.
For metoprolol the following undesirable effects have also been reported: (See Table 3).
![](https://mpfshstrg.blob.core.windows.net/mpf-uat-common-resources/Images/monograph/table.gif)
Isolated cases of arthralgia, hepatitis, muscle cramps, dry mouth, conjunctivitis-like symptoms, rhinitis, impaired concentrations, and gangrene in patients with severe peripheral vascular disease have been reported.
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