Initially 10 mg once daily. If BP is not controlled, may be increased to 20 mg once daily as an optimal dose & may be increased to 40 mg once daily if required.
May potentiate antihypertensive effect by drugs or other agents that lower BP. Additive hyperkalemic effect w/ K supplements, K-sparing diuretics, or other drugs that can cause hyperkalemia. Increased risk of renal impairment & may also attenuate hypotensive effect w/ NSAIDs.
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