Hypotension, tachycardia, and somnolence were the main clinical events seen in a patient who had taken an overdose of 3 g of Quetiapine. Tachycardia of an unexpectedly long duration was also noted. Management was symptomatic, including maintenance of fluids. Asymptomatic prolongation of the QT interval was seen who had taken a 2-g overdose of Quetiapine. The considerable QT interval prolongation may occur when patients overdose on Quetiapine while taking therapeutic doses of Risperidone. Quetiapine overdosage was primarily associated with CNS and respiratory depression and sinus tachycardia.
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