Qvex Special Precautions

Asymptomatic changes in the lens of the eye have occurred in patients during long-term treatment with Quetiapine; Quetiapine should be used with caution in patients with hepatic or renal impairment, with cardiovascular disease or other conditions predisposing to hypotension, with cerebrovascular disease, or with a history of seizures or conditions that lower the seizure threshold.
When Quetiapine is used for the depressive phase in bipolar disorder, patients should be closely monitored during early therapy until significant improvement in depression is observed because suicide is an inherent risk in depressed patients.
Quetiapine may affect the performance of skilled tasks including driving. Gradual withdrawal of quetiapine is recommended because of the risk of withdrawal symptoms, including nausea, vomiting, insomnia, and rebound psychosis, with abrupt cessation.
Effects on ability to drive and use machines: Given its primary central nervous system effects, quetiapine may interfere with activities requiring mental alertness. Therefore, patients should be advised not to drive or operate machinery, until individual susceptibility to this is known.