Ceftriaxone-Sulbactam is used in the treatment of infections caused by susceptible organisms including sepsis, meningitis, abdominal infections (e.g. peritonitis, infections of the biliary tract), infections of the bones, joints, soft tissue, skin and of wounds, renal and urinary tract infections, respiratory tract infections, particularly pneumonia, and ear, nose, and throat infections and uncomplicated gonorrhea.
Ceftriaxone-Sulbactam may also be used for pre-operative prophylaxis of infections. A single dose given pre-operatively may reduce chances of postoperative infection.