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Reproductive studies on Ceftriaxone have been performed in mice and rats at very high doses. No evidence of embryotoxicity, fetotoxicity or teratogenicity was observed. However, in the absence of adequate and well-controlled studies in pregnant women, caution should be taken when using this drug in pregnant women and should only be used if the benefits outweigh the risks.
As Ceftriaxone is secreted in breast milk, caution should be exercised in nursing mothers.
