Treatment of adult patients with newly diagnosed Philadelphia chromosome
positive chronic myeloid leukemia (Ph+ CML) in chronic phase. Patients who have
been treated with nilotinib (Tasigna) for at least 3 years and have achieved a
sustained deep molecular response may be eligible for treatment discontinuation
(see Dosage & Administrations).
Treatment of chronic phase and accelerated phase Philadelphia chromosome
positive chronic myelogenous leukemia (Ph+ CML) in adult patients resistant to or
intolerant to at least one prior therapy including imatinib. Ph+ CML patients in
chronic phase, who have been previously treated with imatinib and whose
treatment has been switched to nilotinib (Tasigna) for at least 3 years and have
achieved a sustained deep molecular response may be eligible for treatment
discontinuation (see Dosage & Administrations).
Treatment of pediatric patients with newly diagnosed Philadelphia chromosome
positive chronic myeloid leukemia (Ph+ CML) in chronic phase.
Treatment of pediatric patients with chronic phase Philadelphia chromosome
positive chronic myeloid leukemia (Ph+ CML) with resistance or intolerance to
prior therapy including imatinib.