Trufix Special Precautions

Cefixime should be administered with caution in patients with markedly impaired renal function. Cefixime should be prescribed with caution in patients with history of gastrointestinal disease, particularly colitis.
A false-positive reaction for ketones in the urine may occur with tests using nitroprusside but not with those using nitroferricyanide. A false-positive reaction to glucose in the urine may occur with Benedict's or Fehling's solution or with copper sulfate test capsules, but not with tests based on enzymatic glucose oxidase reactions. A false-positive direct Coombs test has been reported during treatment with cephalosporin antibiotics, therefore it should be recognized that a positive Coombs test may be due to the drug.
Use in Pregnancy & Lactation: There are no adequate and well controlled studies in pregnant women. Cefixime should therefore not be used in pregnancy or in nursing mothers unless considered essential by the physician.
Use in Children: The safety and efficacy of Cefixime have not been established in children aged less than 6 months.