Precautions in application: Due to intravenous administration in large quantities, rarely, vascular pain and thrombophlebitis may occur. Thus, care should be taken about preparation of solution, injection site, injection method, etc. So, should be injected as slowly as possible.
It is preferable to use freshly constituted solutions of CEFUROXIME for injection. If this is not practicable, solutions for IV injection may be stored for up to 5 hours at room temperature and 48 hours in the refrigerator, and those for IV infusion may be stored for up to 5 hours at room temperature and 48 hours in the refrigerator.