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In very rare instances, it has been felt that haloperidol was contributory to the precipitation of attacks in angina prone patients. Moderate hypotension may occur with excessive oral doses of haloperidol; however, vertigo and syncope occur only rarely.
Haloperidol may lower the convulsive threshold and has been reported to trigger seizures in previously controlled known epileptics.
As with other antipsychotic agents, haloperidol should be administered cautiously to patients with severe impairment of liver or kidney function, and to patients with known allergies to other neuroleptic drugs.
