It is given orally as the oxalate although doses are expressed in terms of the base; Escitalopram oxalate 12.8 mg is equivalent to about 10 mg of Escitalopram.
In the treatment of depression, the usual dose is 10 mg once daily increased, after at least a week, to a maximum of 20 mg once daily if necessary.
For the treatment of panic disorder With or without agoraphobia, initial doses are 5 mg once daily, increased after a week to 10 mg once daily; further increases up to a maximum of 20 mg daily may be necessary in some patients.
Initial treatment with half the usual recommended dose and a lower maximum dose should be considered in elderly patients. Patients with hepatic impairment or those who are poor metaboliser with respect to the cytochrome P450 isoenzyme CYP2C19 may also require lower doses.
Escitalopram should be withdrawn gradually to reduce the risk of withdrawal symptoms.