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Mania: Escitalopram should be discontinued in any patient entering a manic phase.
Paradoxial Anxiety: Some patients with panic disorder may experience increased anxiety symptoms at the start of treatment with antidepressants.
Seizures: Escitalopram should be discontinued in any patient who develops seizures. It should be avoided in patients with unstable epilepsy and patients with controlled epilepsy should be closely monitored.
Diabetes Mellitus: Patients with diabetes mellitus, treatment with Escitalopram may alter glycaemic control, due to improvement of depressive symptoms.
Suicide: As improvement may not occur during the first few weeks or more of treatment, patients should be closely monitored during this period.
Haemorrhage: there have been reports of cutaneous bleeding abnormalities, such as ecchymoses and purpura, with Escitalopram.
