Pregnancy: Pregnancy Considerations: Adverse event were not observed in the initial animal reproduction studied; therefore, the manufacturer classifies ibuprofen as pregnancy category C (category D: ≥30 weeks gestation).
Lactation: Breast-Feeding Consideration: Based on limited data, only very small amounts of ibuprofen are excreted into breast milk. Adverse event have not been reported in nursing infants. Because there is a potential for adverse event to occur in nursing infants, the manufacturer does not recommend the use of ibuprofen while breast-feeding. Use with caution in nursing woman with hypertensive disorders of pregnancy or pre-existing renal disease.