Chotalin Indications/Uses

Edema: Chlorthalidone is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy.
Chlorthalidone has also been found useful in edema due to various forms of renal dysfunction, such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure.
Hypertension: Used alone or in combination with other classes of antihypertensive agents for all stages of hypertension.
Diabetes Insipidus: Thiazides have been used widely in the treatment of diabetes insipidus.
The drugs are effective in both the neurohypophyseal and nephrogenic forms of the disease, decreasing urine volume by up to 50%.
Particularly useful in nephrogenic diabetes insipidus, since this form of the disease is unresponsive to vasopressin or lypressin and chlorpropamide.
Also useful in patients who are allergic or refractory to vasopressin or lypressin and have been used in combination with one of these hormones and a low-salt diet in patients who excrete an exceptionally large volume of urine.