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Use in Pregnancy: Pregnancy Category C: Animal toxicity studies have shown that enoxaparin may have some effect on rat and rabbit reproduction.
There is no information available concerning the use of Clexane during the 1st and 3rd trimesters. As there are no adequate and well-controlled studies in pregnant women and because animal studies are not always predictive of human response, this drug should be used during pregnancy only if the physician has established a clear need.
Use in Lactation: Studies performed in female rats demonstrated that enoxaparin had no effect on lactation or milk composition. Effects of Clexane on lactating women have not been studied.
As a precaution, women should be advised not to breastfeed while using Clexane.
