Sign Out
Central nervous system (CNS) depression-producing medications: concurrent use may potentiate the CNS depressant effects.
Monoamine oxidase (MAO) inhibitors: including furazolidone, phenelzine, procarbazine, selegiline and tranylcypromine; concurrent use with dextromethorphan and also use of MAOI within 2-3 weeks of dextromethorphan may cause adrenergic crisis, collapse, coma, dizziness, excitation hypertension, hyperpyrexia, intracerebral bleeding, lethargy, nausea, psychotic behavior, spasm and tremors.
Amiodarone, Fluoxetine, Quinidine: concurrent use may result increased dextromethorphan serum concentration; high concentrations of dextromethorphan have been associated with increased incidence of side effects.
Sibutramine: concurrent use may result increased serotonergic effects.
