Dextromethorphan hydrobromide, guaifenesin (glyceryl guaiacolate), terpin hydrate.
Each tablet contains Dextromethorphan hydrobromide 20 mg, guaifenesin (glyceryl guaiacolate 50 mg and terpin hydrate 85 mg.
For expectorant and relief of cough caused by common cold and chronic bronchitis.
Adult dose, one tablet 3 times a day or prescribed by physician.
Method of Administration: Oral.
Symptoms: Nausea, vomiting, drowsiness, dizziness, blurred vision, nystagmus, ataxia, shallow respiration, urinary retention, stupor, toxic psychosis and coma, but no fatalities have been reported.
Treatment: Symptomatic and supportive measures, gastric lavage, assisted respiration, vital sign monitoring, parenteral administration of naloxone and oral administration of activated charcoal.
Hypersensitivity to dextromethorphan, guaifenesin, terpin hydrate or any component of the formulation.
D-COATE should not be used for persistent or chronic cough such as with smoking, emphysema, asthma or cough accompanied by excessive secretions, unless directed by physician.
D-COATE should not be used in patients who received MAOI or within 2 weeks after discontinuing MAOI.
D-COATE should not be given during pregnancy unless there are compelling medical reasons. Excretion in breast milk is unknown, please consult the doctor before using D-COATE.
Mild drowsiness, headache, rash, nausea, vomiting, confusion, constipation, GI disturbance, stomach pain, mild dizziness, urticaria.
Central nervous system (CNS) depression-producing medications: concurrent use may potentiate the CNS depressant effects.
Monoamine oxidase (MAO) inhibitors: including furazolidone, phenelzine, procarbazine, selegiline and tranylcypromine; concurrent use with dextromethorphan and also use of MAOI within 2-3 weeks of dextromethorphan may cause adrenergic crisis, collapse, coma, dizziness, excitation hypertension, hyperpyrexia, intracerebral bleeding, lethargy, nausea, psychotic behavior, spasm and tremors.
Amiodarone, Fluoxetine, Quinidine: concurrent use may result increased dextromethorphan serum concentration; high concentrations of dextromethorphan have been associated with increased incidence of side effects.
Sibutramine: concurrent use may result increased serotonergic effects.
Store below 30°C. Protect from heat and moisture.
R05FA02 - opium derivatives and expectorants ; Belongs to the class of combinations of opium derivatives cough suppressants and expectorants. Used in the treatment of cough.
D-Coate tab
50 × 10's;500's
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