Histan Warnings

(Based on the Ministry of Public Health's Announcement): Hydroxyzine hydrochloride is contraindicated in patients with risk factor for cardiac arrhythmias or in combination with other drugs that increase risk of abnormal electrocardiogram e.g. erythromycin.
This medicine should not be used in the elderly and the dose should not exceed 100 mg/day for adults, 50 mg/day for the elderly, or 2 mg/kg/day for children weighing less than 40 kg.
Use the lowest dosage necessary to achieve a therapeutic effect and use for the shortest duration.
This medicine may cause drowsiness therefore should not drive or operate machinery or perform activities which may be at risk of falling from the height.
While using this medicine, should not drink alcohol or anything that is mixed with alcohol.
This medicine can cause dry mouth, dysuria, thick mucus, blurred vision, dizziness and confusion.
Use with caution in combination with CNS suppressants e.g., benzodiazines, anticholinergic drugs and antidepressant drugs.
Use with caution in patients with high blood pressure, cardiovascular disease, hyperthyroid, patients with a history of asthma, or emphysema.
Use in Pregnancy & Lactation: This medicine should not be used in the first trimester pregnancy and breast-feeding.
Use in Children and the Elderly: Children and the elderly are more sensitive to this drug, causing drowsiness, dizziness, hallucinations, dry mouth, urinary retention, low blood pressure, irritability, insomnia and, in some cases, seizures (Paradoxical reaction).