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Pharmacology: Levofloxacin has a wide-spectrum antibacterial effect. Levofloxacin is active against gram-positive and gram-negative bacteria including anaerobes. Moreover, Levofloxacin has shown antibacterial activity against Chlamydia pneumoniae and Mycoplasma pneumoniae.
The main mechanism of action of Levofloxacin is through the inhibition of DNA gyrase (a type II topoisomerase), resulting in inhibition of bacterial DNA synthesis.
