Levofloxacin or any other quinolones is contraindicated in patients who have known hypersensitivity.
Avoid using Levofloxacin in pregnancy and lactation.
If there are any symptoms of rash, muscle pains, hand or Achilles tendonitis, Levofloxacin should be discontinued and consult a physician.
Levofloxacin may be harmful to a kidney or a liver.
Avoid using levofloxacin in patients who have CNS disorders that predispose to seizures. The events are considered to be drug related.
Levofloxacin may prolong QT interval. Use with cautions in such patients who have risk factors such as older ages, existing heart problems, arrhythmic, hypertension or low blood potassium, etc.
Avoid using Levofloxacin with any drugs that prolong QT interval, such as antiarrhythmic class IA (quinidine, procainamide), class III (amiodarone), Cisapride, Erythromycin, Antipsychotics, Tricyclic antidepressants, etc.
Levofloxacin may cause phototoxicity reaction which may be serious, like Toxic Epidermal Necrolysis, Stevens-Johnson Syndrome, Erythema Multiforme, etc.
Levofloxacin may alter blood glucose level. Use with cautions in such patients.
Levofloxacin may increase the pharmacological action of Warfarin.