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Chemistry Properties: Calcitonin is a polypeptide hormone secreted by the parafollicular cells (C cells) of the thyroid gland in mammals. Calcitonin, from any source, is a 32-amino acid polypeptide chain with a disulfide bridge and a molecular weight of about 3600. Prolinamide at the carboxyl terminus, glycine at position 28, and 7 of the first 9 amino acids are common to all calcitonins, but the remaining amino acid sequence may differ considerably from that of human calcitonin, depending on the species.
Mycalcitonin contains a chemical synthetic polypeptide of 32-amino acids in the same linear sequence that found in salmon origin, calcitonin. Potency of salmon calcitonin is expressed in term of International Unit (IU). Each activation of metered dose spray will deliver 0.09 mL of Mycalcitonin solution which contains salmon calcitonin 200 IU.
