It is not recommended to use this product in female patients who are pregnant or who may possibly be pregnant. An animal study (in rats) has shown that the product is transferred to the placenta, and induces a reduction of the number of viable fetuses, a decline in the birthrate, and weight reduction in newborn pups.
For breast-feeding women, continuation or discontinuation of breastfeeding should be considered based on the therapeutic benefits and the benefits of breastfeeding. An animal study (in rats) has shown that the product is excreted in breast milk.