Anticoagulants: Increased prothrombin time (with or without bleeding) has been reported following concomitant use of Cefixime with an anticoagulant (e.g. warfarin).
Carbamazepine: Concomitant administration of Cefixime and carbamazepine has resulted in increased plasma carbamazepine concentrations.
Nifedipine: Concomitant administration of Cefixime and nifedipine increases oral bioavailability of Cefixime as a result of higher peak plasma concentrations and area under the plasma concentration-time curve (AUC).
Probenecid: Concomitant administration of Cefixime and probenecid has resulted in increased effects of Cefixime.