Bladder Cancer: Locally advanced or metastatic bladder cancer, in combination with cisplatin.
Pancreatic Cancer: Locally advanced or metastatic adenocarcinoma of the pancreas.
Non-Small Cell Lung Cancer: First-line treatment of patients with locally advanced or metastatic non-small cell lung cancer, in combination with cisplatin. Gemcitabine monotherapy can be considered in elderly patients or those with performance status 2.
Ovarian cancer: Locally advanced or metastatic epithelial ovarian carcinoma, in combination with carboplatin, in patients with relapsed disease following a recurrence-free interval of at least 6 months after platinum-based, first-line therapy.
Breast Cancer: Unresectable, locally recurrent or metastatic breast cancer, in combination with paclitaxel, in patients experiencing a relapse after adjuvant/neoadjuvant chemotherapy. The preceding chemotherapy should have included an anthracycline, unless clinically contraindicated.