Auget Special Precautions

General: Periodic assessment of organ system functions, including renal, hepatic and hematopoietic function, advisable during prolonged therapy.
Since Auget contains amoxicillin, an aminopenicillin is not the treatment of choice in patients presenting with sore throat or pharyngitis because of the possibility that the underlying cause is infectious mononucleosis, in the presence of which there is a high incidence of rash if amoxicillin is used.
Co-amoxiclav combination should be given with caution to patients with lymphatic leukemia since they are especially susceptible to amoxicillin induced skin rashes.
The possibility of super infections with mycotic or bacterial pathogens should be kept in mind during therapy. If super infections occur (usually involving Aerobacter, Pseudomonas or Candida), the agent should be discontinued and/ or appropriate therapy should be instituted.
Hepatic Impairment: Changes in liver function test have been observed in some patients receiving co-amoxiclav combination. It should be used with care in patients with evidence of severe hepatic dysfunction.
Renal Impairment: In patients with moderate or severe renal impairment the co-amoxiclav combination dosage should be adjusted.
Use in lactation: Amoxicillin is excreted in breast milk. There is no data on the excretion of clavulanic acid in human milk. Trace quantities of clavulanate can be detected in breast milk. With the exception of the risk of sensitization associated with this excretion, there are no known detrimental effects for the breastfed infant.