Cikolin

Citicoline.

Each mL contains: Citicoline 250 mg.

Disturbances of consciousness associated with head injury and brain surgery. Disturbances of consciousness in acute stage of cerebral infarction. Hemiplegia after cerebral apoplexy. Parkinson's disease. Pancreatitis.

Disturbances of consciousness due to head injury or brain surgery: Adult: 100-500 mg once-bid by IV infusion, inj. or IM inj.
Disturbances of consciousness in acute stage of cerebral infarction: 1 g once daily for 2 wk.
Hemiplegia after cerebral apoplexy: 1 g IV once daily for 4 wk or 0.25 g IV once daily for 4 wk & if improvement is observed, another 4 wk.
Parkinson's disease: 0.5 g IV once daily w/ an anticholinergic for 3-4 wk or 0.25-0.5 g 2-3 times/wk in combination w/ an anticholinergic.
Pancreatitis: 1 g IV inj. 2 wk in combination w/ a protease inhibitor.

This preparation contains sodium metabisulfite that may cause serious allergic type reactions in certain susceptible patients.

In cases of patients with conscious disturbance by cephalopathy and/or cerebral operation, it is recommended to treat with antihemorrhagics, blood pressure depressant and hypothermia, etc.
Special Precaution: For the acute, severe case of progressive disturbance of consciousness, antihemorrhagics or brain pressure-decreasing agents should be given concomitantly and the body temperature maintained at a low level.
For patients with disturbance of consciousness in acute stage of cerebral infarction, start of citicoline injection is recommended within 2 weeks after apoplectic stroke.
Use in Elderly: Generally, the elderly is decreased in physiological function. Therefore, caution like dose reduction is recommended.

Use in Pregnancy: Because the safety in pregnant woman is not established, the drug should not be used during pregnancy unless the benefits are considered to outweigh the risks.

Shock: Since shock may rarely occur, close observation should be made. If abnormalities, e.g. dropped blood pressure, chest discomfort and dyspnea are noted, citicoline injection should be discontinued, and appropriate measures taken.
Hypersensitivity: Rash may infrequently occur. In such a case, citicoline injection should be discontinued.
Psychoneurologic System: Insomnia may infrequently occur and headache, dizziness, excitation or convulsions may rarely occur. If citicoline injection is used for the treatment of hemiplegia after cerebral apoplexy, numbness of the paralyzed extremities may occasionally occur or become intensified.
Gastrointestinal System: Nausea may infrequently occur while anorexia may rarely occur.
Liver: Abnormal liver function may infrequently occur.
Eyes: Transient diplopia may rarely occur.
Others: Feeling of warmth may infrequently occur while transient blood pressure changes or malaise may rarely occur.

When the patient is co-administered with levodopa, the effect of levodopa can be increased.

Store at temperatures not exceeding 30°C.

Other CNS Drugs & Agents for ADHD

N06BX06 - citicoline ; Belongs to the class of other psychostimulants and nootropics.

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