Usual Initial & Maintenance Adult Dose: 1 tablet of Losartan 50 mg+ HCTZ 12.5 mg FDC once daily.
For patients who do not respond adequately, adjust to a maximum dose of: 1 tablet of Losartan 100 mg + HCTZ 25 mg FDC daily or, 2 tablets of Losartan 50 mg + HCTZ 12.5 mg FDC daily.
In general, the antihypertensive effect is attained within 3 weeks after initiation of therapy.
Or as prescribed by the physician.